VISDB Viral Integration Site DataBase

VIS ID

TVIS10009462

Fusion event

HBV-MAP7 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2036

Orient

+

Integrated sequence

CTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCC| |TGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGAT

Chromosome

chr6

Cytoband

q23.3

Reference genome

Start

End

136733282/136412144 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-3613-3p ; hsa-let-7c-3p ; hsa-mir-6866-5p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-mir-4766-3p ; hsa-mir-548p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-3646 ; hsa-mir-106a-5p ; hsa-mir-526b-3p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-130a-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-301a-3p ; hsa-mir-493-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-5692a ; hsa-mir-4436b-5p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-3664-3p ; hsa-mir-1304-3p ; hsa-mir-6890-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6741-3p ; hsa-mir-4793-5p ; hsa-mir-205-3p ; hsa-mir-218-1-3p ; hsa-mir-3606-3p ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-659-3p ; hsa-mir-6758-3p ; hsa-mir-9-5p

Nearest miRNA

hsa-mir-10398/Upstream/1172888; hsa-mir-1202/Downstream/2023069;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/51009, chr6-CpG: 160/Downstream/137544

Upstream sequence

atctcgactcactgcaacctctgcctctcaggttcaagcgattctcctgcctcagcctcccgagtagctgagactacaggcgtgcgccaccatgcccagc

Downstream sequence

gccaaggtacttacccacctctgtaagtctcaagctatgaggtgtactttgatttattacctgtaaaatgaggatacaatagaacctatctctcattatt