VISDB Viral Integration Site DataBase

VIS ID

TVIS10009465

Fusion event

HBV-ASS1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1815

Orient

-

Integrated sequence

ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC

Chromosome

chr9

Cytoband

q34.11

Reference genome

Start

End

133325449/130450062 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-324-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-3680-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-5680 ; hsa-mir-3941 ; hsa-mir-606 ; hsa-mir-362-3p ; hsa-mir-329-3p

Nearest miRNA

hsa-let-7a-1/Upstream/208574; hsa-mir-126/Downstream/176235;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/4639, chr9-CpG: 16/Downstream/87441

Nearest cancer related gene

ASS1(TSG, No orient, 0)

Upstream sequence

AAACAAAACTAGATTCTAAGAACTGGCAATTTGACTGGATTTTACATAAAGCTTCAGGGCTGACCAAGGAATTAGATGCAGTTCAGAGATGTGAagcatg

Downstream sequence

CAAACAGGGGTAGGCTTCCACATATTTCCTGAATGCCTTCTGGAGCAGGGGGCAGGAGGCAGGAGGCAGGACAGGTGGCTCTGGGGCTCCTGGACCTCCT