Basic Information
VIS ID
TVIS10009466
Fusion event
HBV-chr9 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1353
Orient
+
Integrated sequence
GCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTAT| |CCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGC
Host Sequence
Chromosome
chr9
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
66849881/40896853 (Hg38)
End
66849881/40896853 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/4003322; hsa-let-7a-1/Downstream/32157;
Nearest TSS
ENST00000422679/Upstream/107577; ENST00000613309/Downstream/176857;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/245073, chr9-CpG: 76/Downstream/94999
Nearby gene
PTGER4P2(-346851) ; LOC286297(+167494) ;
Upstream sequence
ACTGGATTTTACATAAAGCTTCAGGGCTGACCAAGGAATTAGATGCAGTTCAGAGATGTGAagcatgggtagtgcagcaacatggagcactgaaatcaaa
Downstream sequence
acaaatggacatctggagcactttttgtcctatggaagaaaatgaagtatcttcacataaaatctagacagaaacaatctgagaaacttctctgtgatgt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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