Basic Information
VIS ID
TVIS10009468
Fusion event
HBV-LOC105373150 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1136
Orient
+
Integrated sequence
ATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATAC| |CTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCA
Host Sequence
Chromosome
chrX
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
27345369/27327252 (Hg38)
End
27345369/27327252 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105373150
Nearest miRNA
hsa-mir-23c/Upstream/7310065; hsa-let-7f-2/Downstream/1168303;
Nearest TSS
ENST00000429181/Upstream/150954; ENST00000580017/Downstream/71737;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/769197, chrX-CpG: 28/Downstream/536585
Nearby gene
VENTXP1(-766200) ; PPP4R3C(+132959) ;
Upstream sequence
ggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggtgagggttagggttagggttagggttagggttagggtt
Downstream sequence
agtatatgtccataaaaaaacttgtacaagaatgtgcatagcaTGGGAAAATGAGGAATGTTGAGGCAGGATCAGTAGACAGGAGATACATATATgcaca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate