Basic Information
VIS ID
TVIS10009469
Fusion event
HBV-LOC105373150 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
1901
Orient
+
Integrated sequence
TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG| |CATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACC
Host Sequence
Chromosome
chrX
Cytoband
p21.3
Reference genome
End
27345375/27327258 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-23c/Upstream/7310071; hsa-let-7f-2/Downstream/1168297;
Nearby gene
VENTXP1(-766206) ; PPP4R3C(+132953) ;
Upstream sequence
ggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggtt
Downstream sequence
tgtccataaaaaaacttgtacaagaatgtgcatagcaTGGGAAAATGAGGAATGTTGAGGCAGGATCAGTAGACAGGAGATACATATATgcacaagaaaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate