Basic Information
VIS ID
TVIS10009473
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1811
Orient
-
Integrated sequence
AAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAG| |CACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATC
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
10082/10082 (Hg38)
End
10082/10082 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-101-1/Downstream/7287;
Nearest TSS
ENST00000473358/Downstream/19472;
Nearest CpG islands
None/Target, None/Upstream, chr1-CpG: 111/Downstream/18653
Nearby gene
DDX11L1(+1792) ;
Upstream sequence
NNNNNNNNNNNNNNNNNNtaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaac
Downstream sequence
cctaaccctaaccctaaccctaacccaaccctaaccctaaccctaaccctaaccctaaccctaacccctaaccctaaccctaaccctaaccctaacctaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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