Basic Information
VIS ID
TVIS10009537
Fusion event
HBV-chr12 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|precore/core protein|
Start
1814
Orient
-
Integrated sequence
GACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCAC| |CATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGAC
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
95617/10121 (Hg38)
End
95617/10121 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Downstream/1650194;
Nearest TSS
ENST00000382841/Downstream/27981;
Nearest CpG islands
None/Target, None/Upstream, chr12-CpG: 104/Downstream/20668
Nearby gene
WASH8P(-4354) ; FAM138D(+52329) ;
Upstream sequence
ggttagggttagggttagggttaggggttgggttggggtaggggtttgggttaggggttagggttagggttggggtagggttagggttagggttagggtt
Downstream sequence
agggttaaggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttaggg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate