Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009543
Fusion event
HBV-USP50 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
1028
Orient
+
Integrated sequence
ACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCT| |TTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTA
Host Sequence
Chromosome
chr15
Cytoband
q21.2
Reference genome
Start
End
50801368/50509171 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10393/Upstream/148761; hsa-mir-11181/Downstream/733019;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/84542, chr15-CpG: 84/Downstream/176975
Upstream sequence
gcagtgagccaagatcgcgccactgtgctccagcctgggcgacagagcgagactccgtcacaaaaaaaaaaaaaaaaaaaaaaaaaaaaattacaaaatt
Downstream sequence
agctggacatggtgttgtgcctgtagttccatctacttgggaggctgaggtgggaggatggctcgagcctgggaggcagaggttgcagtgagccaagatc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.