VISDB Viral Integration Site DataBase

VIS ID

TVIS10009544

Fusion event

HBV-FBXO22 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

216

Orient

+

Integrated sequence

ATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTC| |TTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGC

Chromosome

chr15

Cytoband

q24.2

Reference genome

Start

End

76228269/75935928 (Hg38)

Orient

-

Location type

downstream

Target gene

miRNAs that regulate target gene

hsa-mir-106b-5p ; hsa-mir-1-3p ; hsa-mir-3671 ; hsa-mir-95-5p ; hsa-mir-5692c ; hsa-mir-5692b

Nearest miRNA

hsa-mir-10393/Upstream/173613; hsa-mir-11181/Downstream/3273860;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/31319, chr15-CpG: 105/Downstream/123415

Upstream sequence

ccaggccggattgcaatggcacaatcttggctcactgcaagctccgcctcccaggttcacgccattctcctgcctcagcctcccgagtagctgggactac

Downstream sequence

aggcgcccgccaccgcgcccggctaattttttgtatttttagtagagacggggtttcaccgtgttagccaagatggtctcgatctcctgaccttgtgatc