Basic Information
VIS ID
TVIS10009559
Fusion event
HBV-chr17 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1730
Orient
-
Integrated sequence
CACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAG| |ACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCAC
Host Sequence
Chromosome
chr17
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
22249114/22749787 (Hg38)
End
22249114/22749787 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/3405213; hsa-mir-10226/Downstream/4544123;
Nearest TSS
ENST00000595228/Upstream/56953; ENST00000583786/Downstream/4250138;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/57105, chr17-CpG: 114/Downstream/3981241
Nearby gene
MTRNR2L1(-225123) ;
Upstream sequence
ttttgaaactctctttctctggaatctgcaaggggacatgcagaactctttgaaggtttcgttggaaacggaatcatcttcacataaaaattacacagaa
Downstream sequence
gcattctcaggaactccttggtgatgtttgtattcaacttccagagttgaactttccttcggaaagagcagctatgaaacactctttttctagaatctgc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate