VISDB Viral Integration Site DataBase

VIS ID

TVIS10009569

Fusion event

HBV-SLC39A11 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

535

Orient

+

Integrated sequence

TTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTA| |CTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAA

Chromosome

chr17

Cytoband

q25.1

Reference genome

Start

End

70976044/72979905 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-375 ; hsa-mir-128-3p ; hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-623 ; hsa-mir-4662a-5p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6832-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-3620-5p ; hsa-mir-1587 ; hsa-mir-6868-3p ; hsa-mir-4291 ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-762 ; hsa-mir-5001-5p ; hsa-mir-4498 ; hsa-mir-4492 ; hsa-mir-6829-5p ; hsa-mir-4656 ; hsa-mir-6882-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-378g ; hsa-mir-6787-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-922 ; hsa-mir-3134 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3184-5p ; hsa-mir-3196 ; hsa-mir-423-5p ; hsa-mir-4459 ; hsa-mir-4519 ; hsa-mir-4534 ; hsa-mir-4722-5p ; hsa-mir-4779 ; hsa-mir-6081 ; hsa-mir-6165 ; hsa-mir-6816-5p ; hsa-mir-8082

Nearest miRNA

hsa-mir-10226/Upstream/3880249; hsa-mir-1250/Downstream/1768708;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/339090, chr17-CpG: 113/Downstream/184878

Upstream sequence

AACCTATGCTACTGCCCAAGGTAGATGGAGGCAAAGCAGCATGCCCTCCTCCCATAACCTGCTCCCCAAAGCGGCAAGCACCCCTCCCATGACTTGCTCC

Downstream sequence

CCAAAGCAGCACACCCACTTCCCATGACCTCCCCAAAATGGTGCATCCTTCTCCCACGACTTGCTGCTGGATCCACTGATTCCTACACCAGCTCTCCAGC