Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009597
Fusion event
HBV-CALCRL integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
44
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAG| |AGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGAC
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
End
188215801/187351074 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/2972030; hsa-mir-1244-1/Downstream/946418;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/501732, chr2-CpG: 106/Downstream/940615
Upstream sequence
AACACATTTGTATGCATAAGAAATATGTTggctgggcgcggtggctcacgcctgtaatcccagcactttgggaggccgaggcgggcggatcacaaggtca
Downstream sequence
ggagatcgagaccatcttggctaacacggtgaaaccccgtctctactaaaaatacaaaaaattagccgggcgcggtggcgggcgcctgtagtcccagcta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.