RFPL1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009613
Fusion event
HBV-RFPL1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|
Start
1883
Orient
-
Integrated sequence
TGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTG| |CCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTA
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
29802103/29406114 (Hg38)
End
29802103/29406114 (Hg38)
Orient
-
Location type
Intronic
Target gene
RFPL1
Nearest miRNA
hsa-mir-1286/Upstream/946166; hsa-let-7a-3/Downstream/600935;
Nearest TSS
ENST00000624155/Upstream/17531; ENST00000354373/Downstream/17065;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/17324, chr22-CpG: 34/Downstream/64223
Nearby gene
AP1B1(-17531) ; RFPL1S(+30901) ;
Upstream sequence
aggagaatggcgtgaacccgggaagcagagcttgcagtgagccgagattgcaccactgcagtccgcagtccggcctgggggacagagcgagactccttct
Downstream sequence
caaaaaaaaaaaaaaaaaaaaaaaaaaaaaaataaaaaaaaaGAAATAACACATCTCTTTCATGAGCTGGAAAGCATCATGCCCATGGAAACAGTGAAGT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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