Basic Information
VIS ID
TVIS10009614
Fusion event
HBV-LINC02042 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
168
Orient
+
Integrated sequence
CTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATC| |ACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTT
Host Sequence
Chromosome
chr3
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
112467562/112748715 (Hg38)
End
112467562/112748715 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02042
Nearest miRNA
hsa-let-7g/Upstream/11534; hsa-mir-12124/Downstream/683403;
Nearest TSS
ENST00000440867/Upstream/99185; ENST00000488781/Downstream/604;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/186612, chr3-CpG: 59/Downstream/242104
Nearby gene
CCDC80(-107585) ; CD200R1L(+66994) ;
Upstream sequence
acaccctacataatccagactctgcttacctctctaacctcatgcaacaccactgtactcttcctgcattatgttccctctagtcactatggccttctct
Downstream sequence
gccaccgcgcccggctaattttttgtatttttagtagagacggggtttcaccgtgttagccaagatggtctcgatctcctgaccttgtgatccgcccgcc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate