Basic Information
VIS ID
TVIS10009631
Fusion event
HBV-chr4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
1936
Orient
-
Integrated sequence
CTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTA| |CTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCC
Host Sequence
Chromosome
chr4
Cytoband
q24
Reference genome
End
103027989/102106832 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/776418; hsa-mir-1243/Downstream/7381866;
Nearby gene
BANK1(-32020) ; SLC39A8(+144209) ;
Upstream sequence
ATCAGAGGCAGCAGTTTTCTTAATGGGGGAAGAATACAAGAGTATAGTTTTCCTTCTGTGCAGTAATTTCTCCATCAAGTTCTTTTATACAGTGGCAATT
Downstream sequence
caaaaaaaaaaaaaaaaaaaattacacaatgagagggagaagaaaagaaaaaactaggaaaaggaatgaagattgcctataagatacagacaactataaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate