VISDB Viral Integration Site DataBase

VIS ID

TVIS10009637

Fusion event

HBV-FAM184B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1881

Orient

-

Integrated sequence

GCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTG| |TGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAG

Chromosome

chr4

Cytoband

p15.31

Reference genome

Start

End

17750121/17748498 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1270 ; hsa-mir-129-5p ; hsa-mir-139-3p ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-4531 ; hsa-mir-620 ; hsa-mir-7850-5p

Nearest miRNA

hsa-mir-12113/Upstream/4120541; hsa-mir-12115/Downstream/2779777;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/39056, chr4-CpG: 91/Downstream/32521

Upstream sequence

caccatcacctctccatgccagttccctctcttgtttgggggaggtccttgtttttctcctcttccattctagcccctgtgtgcacctgctcctccctgc

Downstream sequence

TGTGTAAtttttttttttttttttttttttttttagacaatgtctcgctctgccacccaggctggagtgcagtgtagtggtgatctcggcccactgtagc