VISDB Viral Integration Site DataBase

VIS ID

TVIS10009674

Fusion event

HBV-BTNL9 integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1386

Orient

-

Integrated sequence

GCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAG| |GCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTC

Chromosome

chr5

Cytoband

q35.3

Reference genome

Start

End

180477469/181050469 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-4326 ; hsa-mir-646

Nearest miRNA

hsa-mir-10397/Upstream/6985; hsa-mir-4638/Downstream/172097;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/79906, chr5-CpG: 131/Downstream/2116

Upstream sequence

taaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaac

Downstream sequence

TGCATATAGGGTGTGTTGGCCTTGACACCTGAAAAGTCAGCACCTTGGATATTAGGAACACACTAAGAACGCTACTGAGAACCCAAACAGTCAGTGAGAG