Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009678
Fusion event
HBV-GUSBP3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
1936
Orient
-
Integrated sequence
CTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTA| |CTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCC
Host Sequence
Chromosome
chr5
Cytoband
q13.2
Reference genome
Start
End
68942337/69646510 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/9942807; hsa-mir-103a-1/Downstream/2522957;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/86176, chr5-CpG: 61/Downstream/378687
Upstream sequence
gttccccaggctggagtgcagtggcacgatctcggctcactgcaacctccacatcccaggttcaagcaattcttctgcctcagcctcccaagtagctgag
Downstream sequence
ttttttaattttttttttttttttttttttttttttttttgagatggagtctcactgtcacccaggctggagtgtagtgctgcgatcctgactcgctgca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.