VISDB Viral Integration Site DataBase

VIS ID

TVIS10009682

Fusion event

HBV-VCAN integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1814

Orient

-

Integrated sequence

GACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCAC| |CATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGAC

Chromosome

chr5

Cytoband

q14.3

Reference genome

Start

End

82811939/83516120 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-545-3p ; hsa-mir-5197-3p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-218-5p ; hsa-mir-578 ; hsa-mir-3185 ; hsa-mir-643 ; hsa-mir-335-3p ; hsa-mir-4436b-5p ; hsa-mir-627-3p ; hsa-mir-6777-3p ; hsa-mir-5003-3p ; hsa-mir-23b-3p ; hsa-mir-129-5p ; hsa-mir-302c-5p ; hsa-mir-361-3p ; hsa-mir-3680-3p ; hsa-mir-450b-5p ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-507 ; hsa-mir-552-5p ; hsa-mir-557

Nearest miRNA

hsa-mir-10397/Upstream/675896; hsa-mir-103a-1/Downstream/3598759;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/41340, chr5-CpG: 59/Downstream/205955

Upstream sequence

CGAGTGATTGTGTAAACCCAGGCCTGAAGTTATACTTTATTAAGGTAAATCATGCTGATTTTCAGCTTTCACTGAAGATTTACCTTTTCCTTGATGATCT

Downstream sequence

cctaacccaaaccctaaccctaaccctaaccctatccctagcctgtagtcccagtcgggaggctgaggcaggagaatggcgtgaacctgggaggtggagc