VISDB Viral Integration Site DataBase

VIS ID

TVIS10009690

Fusion event

HBV-CD109 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

162

Orient

+

Integrated sequence

TGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAG| |AACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGT

Chromosome

chr6

Cytoband

q13

Reference genome

Start

End

74469944/73760221 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-4482-3p ; hsa-mir-6807-5p ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-449b-3p ; hsa-mir-103a-2-5p ; hsa-mir-3124-3p ; hsa-mir-186-3p

Nearest miRNA

hsa-mir-10398/Upstream/792468; hsa-mir-10524/Downstream/1668186;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/63810, chr6-CpG: 28/Downstream/1324943

Upstream sequence

gtaATTTtgagaggtgaagccagctgggcttctgggtcaggtggggacttggagaacttttctgtctagctaaaggattgtaaacgcaccaatcagcact

Downstream sequence

acggtgaaaccccgtctctactgaaaatacaaaaaattagccgggcgcggtggcgggcgcctgtagtcccagctactcgggaggctgaggcaggagaatg