Basic Information
VIS ID
TVIS10009691
Fusion event
HBV-chr6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
78
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCA| |GGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGAT
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
End
86091086/85381368 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/6842059; hsa-mir-1202/Downstream/4931374;
Nearby gene
TBX18(-617187) ; NT5E(+68216) ;
Upstream sequence
agaagaaatagataacctgaatagccatatagctattaaagaaatcagaattatcaatacaaatcgtcccacaaagaaaactGGATTTTATCATCAATAT
Downstream sequence
aaaaatacaaaaaattagccgggcgcggtggcgggcgcctgtagtcccagctactcgggaggctgaggcaggagaatggcgtgaacctgggaggcggagc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate