Basic Information
VIS ID
TVIS10009694
Fusion event
HBV-LOC107986854 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1032
Orient
+
Integrated sequence
AAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTA| |CACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACA
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
GRCh37/hg19
Start
139934292/140234492 (Hg38)
End
139934292/140234492 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107986854
Nearest miRNA
hsa-mir-10399/Upstream/1190335; hsa-mir-11400/Downstream/2240035;
Nearest TSS
ENST00000635602/Upstream/57457; ENST00000495590/Downstream/103333;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/3203, chr7-CpG: 26/Downstream/58029
Nearby gene
KDM7A-DT(-54852) ; SLC37A3(+99260) ;
Upstream sequence
AAATttggaagccacatgatgaaaagacaaagccccaaattaggtgtctgagtctctgagttactacatagagaagagcagcccATCAATCAGGTCATTA
Downstream sequence
CAggccagatgcagtgggctcatgcctgtaatcccagcactttgggaggccaaggcaggtggatcacctgaggtcaggagtttgagaccagcctagccaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate