VISDB Viral Integration Site DataBase

VIS ID

TVIS10009714

Fusion event

HBV-NUP188 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1936

Orient

-

Integrated sequence

CTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTA| |CTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCC

Chromosome

chr9

Cytoband

q34.11

Reference genome

Start

End

131750990/128988711 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-324-5p ; hsa-mir-93-5p ; hsa-mir-31-5p ; hsa-mir-20a-5p ; hsa-mir-4752 ; hsa-mir-6833-5p ; hsa-mir-7847-3p ; hsa-mir-1183

Nearest miRNA

hsa-let-7a-1/Upstream/595997; hsa-mir-12126/Downstream/880894;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/40426, chr9-CpG: 32/Downstream/39158

Upstream sequence

TTGTATATTTGAGGGGAAAGTAGAAAAACCAAGCCAAGATTTTAAAAATTACATTTACTATCACCATCTCCAAGTTACATTCACTATAGAATCCTTTAGA

Downstream sequence

ttttttaatttttttttttttttttttttttttttgagacagtctagctctgttgcccaggctggagtgcagtggcgcaatctcggcttactgcagcatc