Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009716
Fusion event
HBV-TUBBP5 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1814
Orient
-
Integrated sequence
GACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCAC| |CATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGAC
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
End
141054317/138159865 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-let-7a-1/Upstream/321349;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/9204, chr9-CpG: 62/Downstream/15078
Upstream sequence
GAATATGGCTGAGCCATCATCCGTTCTatggttggatagatggatgcatgaatgggtggatggatgggtggatgggttgattggatggatgagagatggc
Downstream sequence
agggctagggttggggtcagtggttaggggtcatggttaagggttaagggttggggttgggggttagggttaggggttagggtaagggttaaggctaagg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.