Basic Information
VIS ID
TVIS10009719
Fusion event
HBV-chr9 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
11
Orient
+
Integrated sequence
AATTCCACAAC| |CTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCT
Host Sequence
Chromosome
chr9
Cytoband
p13.1
Reference genome
End
67587641/38844084 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/1950553; hsa-let-7a-1/Downstream/2084926;
Nearby gene
AQP7P1(-298149) ; FAM27B(+205288) ;
Upstream sequence
AACCTACATTGGTGAATTGTTTGAGTATGTTTGTGAGGTCAGTTGGTGGCTCATAAAGAGACATTCCTATGTCCAAAGATCCAAATAAAATATAATTCCA
Downstream sequence
cccgggaagcggagcttgcagtgaaccgagattgcgccactgcagtccgcagtccggcctgggcgacagagcgagactccgtctcaaaaaaaaaaaaaaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate