Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009731
Fusion event
HBV-FGF13 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1823
Orient
-
Integrated sequence
TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAA
Host Sequence
Chromosome
chrX
Cytoband
q26.3
Reference genome
End
137949906/138867744 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7f-2/Upstream/199951; hsa-mir-105-1/Downstream/1056404;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/155896, chrX-CpG: 40/Downstream/326921
Upstream sequence
gctgaagcaggagaatggcgtgaacccgggaggcagagcttgcagtgagccgagatcgcgccactgcactccagcctgggcgacagagcgagactccgtt
Downstream sequence
tgggtgggaacacagccaaaccgtatcaCTGTCTCTAAatctatctatctatctatctatctatctatctatctatctatctatctatcatctatctatc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.