Basic Information
VIS ID
TVIS10009742
Fusion event
HBV-chrX integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1690
Orient
-
Integrated sequence
CTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACG| |ACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGC
Host Sequence
Chromosome
chrX
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
58570767/58544334 (Hg38)
End
58570767/58544334 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/3092752; hsa-mir-105-1/Downstream/5241668;
Nearest TSS
ENST00000429181/Upstream/633514; ENST00000451979/Downstream/4805312;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/633847, chrX-CpG: 51/Downstream/4806739
Nearby gene
ZXDA(-633700) ;
Upstream sequence
gtttttgtttttttttttttttttgagatggagtctggctctgtcgcccaggctggagtgcagtggcacgatctcagctcactgcaatctccacctccca
Downstream sequence
atacaaacatcacaaagtagtttccgagaatgcttctgtttagttcttatgtgaagatgatcccgtttccagtgaaatcttcaaagaggtccacatatcc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate