VISDB Viral Integration Site DataBase

VIS ID

TVIS10009758

Fusion event

HBV-ARHGEF11 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

802

Orient

-

Integrated sequence

TTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGT| |TACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTAT

Chromosome

chr1

Cytoband

q23.1

Reference genome

Start

End

156976482/157006690 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-5011-5p

Nearest miRNA

hsa-mir-101-1/Upstream/70446; hsa-mir-1182/Downstream/2893289;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/78686, chr1-CpG: 86/Downstream/38814

Upstream sequence

TCTGGTGCAGAAGACAGCTCTGGCCTGGGGCTCAATACTTTGGTTCTTGGTAACAGCATGGGAAGTCAGGCAGATCTGGCTTTCCAGACAATTGGATAGG

Downstream sequence

GCTCAGGTCAGAAAGGCAGAGACTGAGAAAAGTTTCACCATCTGCTGGCACCTCCTTCCCTGGATCACACTGAACCTTTAACGATTTGACTGGTATGTGA