VISDB Viral Integration Site DataBase

VIS ID

TVIS10009759

Fusion event

HBV-PPP1R12B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2675

Orient

+

Integrated sequence

AAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATT| |TACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTAT

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

202355183/202386055 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-30b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-29a-5p ; hsa-mir-659-3p ; hsa-mir-92a-1-5p ; hsa-mir-1228-3p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-188-5p ; hsa-mir-2114-3p ; hsa-mir-30b-3p ; hsa-mir-3160-3p ; hsa-mir-3192-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3689d ; hsa-mir-377-5p ; hsa-mir-4487 ; hsa-mir-455-3p ; hsa-mir-4661-3p ; hsa-mir-4728-5p ; hsa-mir-4780 ; hsa-mir-558 ; hsa-mir-6086 ; hsa-mir-6134 ; hsa-mir-623 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6780b-3p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6807-5p ; hsa-mir-6823-3p ; hsa-mir-6851-5p ; hsa-mir-6866-3p ; hsa-mir-6880-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-7847-3p

Nearest miRNA

hsa-mir-101-1/Upstream/382819; hsa-mir-1182/Downstream/3062247;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/36987, chr1-CpG: 104/Downstream/256485

Upstream sequence

cggagtcttgctctgtcacccaggctggagtgcagtggcacgatcttggctcactgcaagctccacctcccgggttcacaccattctcctgcctcagcct

Downstream sequence

ccctagtagctgggactacaggcgcccgccaccatgcccggctaattttttgtgttttcggtagagacggggtttcaccgtgttagccaggatagtctca