VISDB Viral Integration Site DataBase

VIS ID

TVIS10009760

Fusion event

HBV-PPP1R12B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1817

Orient

-

Integrated sequence

TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT| |GCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCT

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

202469563/202500435 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-30b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-29a-5p ; hsa-mir-659-3p ; hsa-mir-92a-1-5p ; hsa-mir-1228-3p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-188-5p ; hsa-mir-2114-3p ; hsa-mir-30b-3p ; hsa-mir-3160-3p ; hsa-mir-3192-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3689d ; hsa-mir-377-5p ; hsa-mir-4487 ; hsa-mir-455-3p ; hsa-mir-4661-3p ; hsa-mir-4728-5p ; hsa-mir-4780 ; hsa-mir-558 ; hsa-mir-6086 ; hsa-mir-6134 ; hsa-mir-623 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6780b-3p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6807-5p ; hsa-mir-6823-3p ; hsa-mir-6851-5p ; hsa-mir-6866-3p ; hsa-mir-6880-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-7847-3p

Nearest miRNA

hsa-mir-101-1/Upstream/497199; hsa-mir-1182/Downstream/2947867;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/151367, chr1-CpG: 104/Downstream/142105

Upstream sequence

ttaaatgtccattaacagatgaacagataaattaaatgtggtatatgtacatagtggaatactatttagccataaagaaaaatgaaattatgtcattcac

Downstream sequence

agcaacatgaatgatcctggaagccattatgttaggtgaaataagtcagtcacagaaaaataaatacctcatgttctctctcatatgtaggatcttaaaa