VISDB Viral Integration Site DataBase

VIS ID

TVIS10009762

Fusion event

HBV-PIK3R3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1789

Orient

-

Integrated sequence

GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG| |CATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGG

Chromosome

chr1

Cytoband

p34.1

Reference genome

Start

End

46540528/46074856 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-18a-3p ; hsa-mir-346 ; hsa-mir-331-3p ; hsa-mir-7-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-148b-3p ; hsa-mir-193a-5p ; hsa-mir-132-3p ; hsa-mir-152-3p

Nearest miRNA

hsa-mir-12136/Upstream/1529304; hsa-mir-101-1/Downstream/4984981;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/270708, chr1-CpG: 84/Downstream/57598

Upstream sequence

cccagcctcatcagggtcttcccacacatccccatccaaacgtatagaattccatctttcccaaccaatgccctcattttaacagcagataccttacaag

Downstream sequence

gctgatatttcacctttgattgtaattcagctaatcacatgatgagagtatgtgtttgattttgtgcaatttcagacctttggcaacagaagagaagatt