Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009773
Fusion event
HBV-TTC23 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1821
Orient
+
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
Start
End
99759205/99219000 (Hg38)
Orient
-
Location type
Exonic
Target gene
Nearest miRNA
hsa-mir-10393/Upstream/434498; hsa-mir-1302-10/Downstream/2741459;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/112761, chr15-CpG: 64/Downstream/32123
Upstream sequence
TGAAGGGAGAGTAAAGCTCTGCCCATGGTATGGAAAAGCTCAATGGAAAACTTGAAAACATCTGTATTCTCACTATAGGGAGGCACAATGGAGTTGGCGA
Downstream sequence
GGATTTGTCTGGCTTTTTCTGCATGTTGTTTTGCTTGCAGTGACAGTCCTGTGGACAAAGAAAAAGAGGTCTCAGTTTCTCTATCATCTCAACTGGACAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.