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VISDB
Viral Integration Site DataBase
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TVIS10009781
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009781
Fusion event
HBV-CPS1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|
Start
1839
Orient
+
Integrated sequence
AGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTA| |ATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTG
Host Sequence
Chromosome
chr2
Cytoband
q34
Reference genome
GRCh37/hg19
Start
211431648/210566924 (Hg38)
End
211431648/210566924 (Hg38)
Orient
+
Location type
Intronic
Target gene
CPS1
miRNAs that regulate target gene
hsa-mir-17-5p
;
hsa-mir-3121-3p
;
hsa-mir-4255
;
hsa-mir-4709-3p
;
hsa-mir-7154-5p
;
hsa-mir-101-3p
;
hsa-mir-1255b-5p
;
hsa-mir-1255a
;
hsa-mir-6744-5p
;
hsa-mir-8060
;
hsa-mir-16-1-3p
;
hsa-mir-144-3p
;
hsa-mir-216a-5p
;
hsa-mir-522-3p
;
hsa-mir-224-3p
;
hsa-mir-4694-3p
;
hsa-mir-6516-5p
;
hsa-mir-6738-3p
;
hsa-mir-1303
;
hsa-mir-3678-3p
;
hsa-mir-1273h-3p
;
hsa-mir-5001-3p
;
hsa-mir-4727-5p
;
hsa-mir-1200
;
hsa-mir-142-3p
;
hsa-mir-630
;
hsa-mir-146b-3p
;
hsa-mir-6799-3p
;
hsa-mir-3173-5p
;
hsa-mir-7976
;
hsa-mir-496
;
hsa-mir-302a-5p
;
hsa-mir-18a-3p
;
hsa-mir-324-3p
;
hsa-mir-1913
;
hsa-mir-4682
;
hsa-mir-544b
;
hsa-mir-4324
;
hsa-mir-4778-5p
;
hsa-mir-200b-5p
;
hsa-mir-200a-5p
;
hsa-mir-4796-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-548l
;
hsa-mir-8054
;
hsa-mir-548k
;
hsa-mir-548av-5p
;
hsa-mir-548c-3p
Nearest miRNA
hsa-mir-10b/Upstream/2812043; hsa-mir-1244-1/Downstream/1859339;
Nearest TSS
ENST00000437798/Upstream/10190;
ENST00000497163/Downstream/10231;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/90112
,
chr2-CpG: 86/Downstream/1970532
Upstream sequence
ATGTTAACTGTTATTAAGGATGTCATAGGGAATTGATCAGAATGGAGTTCTCGGTGACACAACATGCTCCCAAACCTTACTTTTCCAACATAGCTTCATA
Downstream sequence
ATTCTGTTTGAAGTAAGATACCTTTCCCAGAACAGTATAAATTTATTATTCAAATCCAAATTCTCAACTTATTTGTACAACTGCATATAGACTTTAATAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Sample Information
×
Sample name
734P
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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