Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009787
Fusion event
HBV-DNAH6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2659
Orient
+
Integrated sequence
ACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCA| |AAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTC
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
Start
End
84923501/84696377 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/4829794; hsa-mir-10b/Downstream/1087223;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/179816, chr2-CpG: 77/Downstream/184230
Upstream sequence
ATAAGCTGTACTCGTAACATTCTTTGCCCATGCTTTAATTAAGGGAGAAATTAATGATGTGTCTTAGGACTTTAAAACATTCATATAAAGATCAAGAAAG
Downstream sequence
TCAAAATCTCTTAGAGACTAAGAAAAATGAACTTAATATAAATAAAAATCTATGGAATGCAACCCAGCAGTTCTCAAATTTACATTTGTAGATTTGAATC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.