Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009793
Fusion event
HBV-RFTN1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
587
Orient
+
Integrated sequence
CAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGA| |CGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTG
Host Sequence
Chromosome
chr3
Cytoband
p24.3
Reference genome
Start
End
16406796/16365289 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12127/Upstream/491440; hsa-let-7g/Downstream/567907;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/99810, chr3-CpG: 113/Downstream/147531
Upstream sequence
aatcaaatgatatacacaatattcagaatagatattagcttttcaaagaaagaaaatgattgagatttggggcaagagcatacaagtttgccaagacata
Downstream sequence
TTCCCTCACCACCACTGGCATTATTGAGCATCATCCAGAACTATCATTAGCCACCTTCTGAATACAGCACTGTGATGTTAAGAAAGTACAAAAAGTAGGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.