Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009798
Fusion event
HBV-ALB integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1841
Orient
+
Integrated sequence
TTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAAT| |CATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTG
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
Start
End
74270526/73404809 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/7127881; hsa-mir-1243/Downstream/3168759;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/145396, chr4-CpG: 20/Downstream/215518
Upstream sequence
tataccacattttctttatccagtcaacaattgatgggcacctagattgattccatacctttgttattgtgaatagtgctgcaatgaacatacaagtaac
Downstream sequence
TTAGTCTGTCTTCTTGGTTGCTGTTGATAGACACTAAAAGAGTATTAGATATTATCTAAGTTTGAATATAAGGCtataaatatttaataatttttaaaat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.