Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009803
Fusion event
HBV-SLC17A4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1765
Orient
-
Integrated sequence
TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAG| |GTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGT
Host Sequence
Chromosome
chr6
Cytoband
p22.2
Reference genome
Start
End
25755772/25755544 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-3691/Upstream/7183664; hsa-mir-10398/Downstream/1392082;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/22815, chr6-CpG: 24/Downstream/126555
Upstream sequence
CTCAAGGATGCCAAGGGTCTAGGGTATAACATAAAATCAGTATCTTGGATAAGACAAACAGGTATTAAATAAAAATGGAAAGAAAGTCTATTAACAGTGA
Downstream sequence
AAGAACAGACACAAGCAGTCTTGGCAAGAAAAACTGATGAGAAATTGATATAAGAATGGCTGGCTCCATTTCTTTGCTGTTTTTTCCTCATTTACCTGGT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.