Fusion event
HBV-chr10 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|Polymerase|
Integrated sequence
CACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCA| |ACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAA
End
88512748/86752991 (Hg38)
Nearest miRNA
hsa-mir-1265/Upstream/488203; hsa-mir-107/Downstream/750890;
Nearest cancer related gene
Upstream sequence
CCTCAAGGCCTAGGAAAGATCAGGTTCTATGGTAAAGGGTGTACGGATAGTAGGGAAAGGAGGAATACAGAGGCCACGGACTAGGTAGGACCAAGTGAGA
Downstream sequence
GCAGCAATATCCTCCATCATCTATCTTTCAATCATAGTAGCCAGTGCTTTGAGGCAAAGATAAATTAAAATGGAGCTAAGGGAGAAGGAGCAAGTTGTTT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.