VISDB Viral Integration Site DataBase

VIS ID

TVIS10009827

Fusion event

HBV-MARCH2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

903

Orient

-

Integrated sequence

ACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATG| |GGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGT

Chromosome

chr19

Cytoband

p13.2

Reference genome

Start

End

8499196/8434312 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-377-3p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-345-3p ; hsa-mir-141-5p ; hsa-mir-6768-5p ; hsa-mir-6732-3p ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-1227/Upstream/44932; hsa-let-7e/Downstream/1604042;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/3402, chr19-CpG: 118/Downstream/10439

Upstream sequence

tagctgggattacaggcatgtgccaccacacccagccaatttttatatttttagtagagacggggtttcgccatgttggccaggctggtctcgaactctt

Downstream sequence

gacctcaggtatccacccaccttggccttccaaagtgctgagattacaggcatgaaccatcgcgccctgccCCTACCAGCATATTTTAAAATATGTAAAT