VISDB Viral Integration Site DataBase

VIS ID

TVIS10009843

Fusion event

HBV-DLGAP2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

784

Orient

-

Integrated sequence

GTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGA| |GTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGT

Chromosome

chr8

Cytoband

p23.3

Reference genome

Start

End

1332927/1384761 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-20a-3p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-4764-5p ; hsa-mir-627-3p ; hsa-mir-4635

Nearest miRNA

hsa-mir-10400/Downstream/416364;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/5380, chr8-CpG: 58/Downstream/8293

Nearby gene

LOC286083(-82100) ; DLGAP2(+116642) ;

Upstream sequence

ctggacaggtagagtgcaagtacttgcctccctgagtctctgtctcatcctgggagatagggtgacagtggccttataggactgttgctgtggaggtcaa

Downstream sequence

CCGGCCCCTGAGAACTTGGTGCACAGTTACCCCGGCCTGTGCCCGTCCCCTGAGAACTTGGTGCACAGTTACCCCGGCCTATGCCCGTCCCCTGAGAACT