VISDB Viral Integration Site DataBase

VIS ID

TVIS10009854

Fusion event

HBV-PCNX2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1803

Orient

-

Integrated sequence

CATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTG| |CGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCA

Chromosome

chr1

Cytoband

q42.2

Reference genome

Start

End

233330654/233194908 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-154-5p ; hsa-mir-382-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-3613-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-4324 ; hsa-mir-4277 ; hsa-mir-584-3p ; hsa-mir-6874-3p ; hsa-mir-148b-5p ; hsa-mir-383-5p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-1304-3p ; hsa-mir-5007-5p ; hsa-mir-3664-5p ; hsa-mir-4797-5p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-6506-5p ; hsa-mir-4731-5p ; hsa-mir-619-5p ; hsa-mir-6504-3p ; hsa-mir-1283 ; hsa-mir-4438 ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-1200 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4714-3p ; hsa-mir-4722-3p ; hsa-mir-498 ; hsa-mir-544b ; hsa-mir-660-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6869-5p

Nearest miRNA

hsa-mir-101-1/Upstream/2174984; hsa-mir-1537/Downstream/429244;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/208518, chr1-CpG: 38/Downstream/100495

Upstream sequence

gattgagatcatcctagctaacatggtgaaaccccatctctactaaaaaatacaaaaaattaactgggcgtggtggtgggctcctgtagtcccagctact

Downstream sequence

ggggaggctgaggcaggagaatggcgtgaacccaggaggtggagcttgcagtgagccaagatcacgctgccgcactccagcctgggtaacagagtgagat