VISDB Viral Integration Site DataBase

VIS ID

TVIS10009855

Fusion event

HBV-SMYD3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1727

Orient

-

Integrated sequence

GCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTA| |AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT

Chromosome

chr1

Cytoband

q44

Reference genome

Start

End

245938928/245775626 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-218-5p

Nearest miRNA

hsa-mir-101-1/Upstream/2429371; hsa-mir-3124/Downstream/1426341;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/86414, chr1-CpG: 132/Downstream/198847

Upstream sequence

agtcatcaccactccctaatctcaagtacccagggacacaaacactgcggaaggccgcagggtcctctgcctaggaaaaccagagacctttgttcacctg

Downstream sequence

tttatctgccgaccttccctccactattgtcctatgaccctgccaaatccccctctccgagaaacacccaagaatgatcaataaatactaaaaaaaaaaa