VISDB Viral Integration Site DataBase

VIS ID

TVIS10009861

Fusion event

HBV-SPATA6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1727

Orient

-

Integrated sequence

GCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTA| |AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT

Chromosome

chr1

Cytoband

p33

Reference genome

Start

End

48847476/48381804 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-7109-5p ; hsa-mir-4463 ; hsa-mir-370-3p ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-6867-5p ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-6766-5p ; hsa-mir-92a-2-5p ; hsa-mir-6756-5p ; hsa-mir-6747-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-4723-5p ; hsa-mir-5698 ; hsa-mir-625-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-765 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-4670-3p ; hsa-mir-7155-5p ; hsa-mir-5571-5p ; hsa-mir-574-5p ; hsa-mir-3650 ; hsa-mir-297 ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-520f-5p ; hsa-mir-511-3p ; hsa-mir-548p

Nearest miRNA

hsa-mir-12136/Upstream/3836252; hsa-mir-101-1/Downstream/2678033;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/383875, chr1-CpG: 67/Downstream/89828

Upstream sequence

tttatttattttttattgatcattcttgggtgtttctcgcagagggggatttagcagggtcataggacaatagtggagggaaggtcagcagataaacaag

Downstream sequence

tgaacaaaggtctctggttttcctaggcagaggaccctgcggccttggccttccgcagtgtttgtgtccctgggtacttaagattagggagtggtgatga