VISDB Viral Integration Site DataBase

VIS ID

TVIS10009864

Fusion event

HBV-SERBP1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1666

Orient

-

Integrated sequence

ATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACT| |CTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGG

Chromosome

chr1

Cytoband

p31.3

Reference genome

Start

End

67892464/67426781 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-26a-5p ; hsa-mir-10a-5p ; hsa-mir-16-5p ; hsa-mir-93-3p ; hsa-mir-652-3p ; hsa-mir-625-5p ; hsa-mir-615-3p ; hsa-mir-505-3p ; hsa-mir-328-3p ; hsa-mir-374a-5p ; hsa-mir-30b-5p ; hsa-mir-15b-5p ; hsa-mir-100-5p ; hsa-mir-27a-3p ; hsa-mir-18a-5p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-8485 ; hsa-mir-548n ; hsa-mir-4699-3p ; hsa-mir-6509-5p ; hsa-mir-6732-3p ; hsa-mir-450b-5p ; hsa-mir-6750-3p ; hsa-mir-6512-5p ; hsa-mir-433-3p ; hsa-mir-7154-5p ; hsa-mir-4443 ; hsa-mir-1273e ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6134 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-219b-3p ; hsa-mir-1247-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-2054 ; hsa-mir-302f ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4799-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-4723-5p ; hsa-mir-5698 ; hsa-mir-8059 ; hsa-mir-4471 ; hsa-mir-651-5p ; hsa-mir-4715-3p ; hsa-mir-885-5p ; hsa-mir-22-3p ; hsa-mir-6802-5p ; hsa-mir-6800-5p ; hsa-mir-4645-3p ; hsa-mir-4790-3p ; hsa-mir-622 ; hsa-mir-3177-5p ; hsa-mir-5093 ; hsa-mir-875-3p ; hsa-mir-4308 ; hsa-mir-511-3p ; hsa-mir-504-5p ; hsa-mir-1257 ; hsa-mir-8060 ; hsa-mir-664a-3p ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-548l ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p ; hsa-mir-4501 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-513a-5p ; hsa-mir-4733-3p ; hsa-mir-370-5p ; hsa-mir-4764-3p ; hsa-mir-510-5p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-4462 ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-7845-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p

Nearest miRNA

hsa-mir-101-1/Upstream/798264; hsa-mir-11399/Downstream/756737;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/291749, chr1-CpG: 139/Downstream/2671

Upstream sequence

TACATTTTGGCTTTTAAAATACCAAAGAAAATACCAGCAGCCATTCATAAATAACCAAGCAAATCAACACACTCACTAGATATGGCCCCTCACAAAAGTG

Downstream sequence

AGGGCCGCACTATGTTATTCTATCTAATCTGAAAAAAAAATGCAATTAAGACTCATAATTCTATAAAATTACAAATCTGAAAGGAAAATATGGCATTTAG