VISDB Viral Integration Site DataBase

VIS ID

TVIS10009880

Fusion event

HBV-TEAD1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2758

Orient

-

Integrated sequence

AAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACT| |CTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAG

Chromosome

chr11

Cytoband

p15.3

Reference genome

Start

End

12768512/12746965 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-98-5p ; hsa-mir-320a ; hsa-mir-215-3p ; hsa-mir-503-3p ; hsa-mir-548at-5p ; hsa-mir-873-5p ; hsa-mir-101-5p ; hsa-mir-377-3p ; hsa-mir-1324 ; hsa-mir-5004-3p ; hsa-mir-1261 ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-624-3p ; hsa-mir-548e-5p ; hsa-mir-7150 ; hsa-mir-580-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6077 ; hsa-mir-5580-5p ; hsa-mir-219a-1-3p ; hsa-mir-6868-5p ; hsa-mir-9500 ; hsa-mir-4267 ; hsa-mir-4445-3p ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-494-3p ; hsa-mir-548p ; hsa-mir-561-3p ; hsa-mir-5187-3p ; hsa-mir-6515-3p ; hsa-mir-1236-3p ; hsa-mir-3140-5p ; hsa-mir-4713-5p ; hsa-mir-3156-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-4301 ; hsa-mir-181a-2-3p

Nearest miRNA

hsa-mir-210/Upstream/583198; hsa-let-7a-2/Downstream/3222568;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/71531, chr11-CpG: 198/Downstream/261818

Upstream sequence

AGGCTGCAGCAGGGGCTGGGATGCCACAGACCAGGCGGGCTGGGGGTTCACCAGTGAAGACCTCAGACTGTGCGGCTCAGCAGGTGGCAGGTCCTGCCTG

Downstream sequence

AGGTTAAAGAAAGGTGGAGTTGGTTGTTGAGGCCACAGACCAGGTAGTCAGGGTGTTTGGAAACCTGAGGAAGGTTTTGAGGCCAGTGAGTCTCTTTTAT