SCGB1C1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009883
Fusion event
HBV-SCGB1C1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
639
Orient
-
Integrated sequence
TCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTC| |CTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTA
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
191837/191837 (Hg38)
End
191837/191837 (Hg38)
Orient
-
Location type
Intronic
Target gene
SCGB1C1
Nearest miRNA
hsa-let-7a-2/Downstream/17499;
Nearest TSS
ENST00000527297/Upstream/52225; ENST00000342878/Downstream/1243;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/64060, chr11-CpG: 184/Downstream/15138
Nearby gene
LINC01001(-59917) ; SCGB1C1(+1243) ;
Upstream sequence
caagaactcttttcattgccagtggaaCACAGCGTATAAGACCAAAATACGCCACCCCAAAAcctaaccctaaccctaacccctaacccctaaccctaac
Downstream sequence
cctaaccctaaccctaacccctaacccctaaccctaaccctaaccctaacccctacccctaacccctaacccttaccggtgaccctactgtatccctgac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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