VISDB Viral Integration Site DataBase

VIS ID

TVIS10009884

Fusion event

HBV-BBOX1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

841

Orient

+

Integrated sequence

TGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCC| |TAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAA

Chromosome

chr11

Cytoband

p14.2

Reference genome

Start

End

27065031/27043484 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6505-5p ; hsa-mir-4477a ; hsa-mir-616-3p ; hsa-mir-5583-3p

Nearest miRNA

hsa-mir-210/Upstream/3624294; hsa-let-7a-2/Downstream/471486;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/711219, chr11-CpG: 29/Downstream/319588

Upstream sequence

tttaagtgctggggtacatgtgcagaatgtgcacgtttggggtacatgtgcagaatgtgcaggtttggggtacacgtgcagaatgtgcaggtatacacat

Downstream sequence

gccatggtggtttgctgcacctatcaacgcgtcatctacattgaataccctttatttctttctcttgactaattgccctagcatttctcctaatggtatc