VISDB Viral Integration Site DataBase

VIS ID

TVIS10009901

Fusion event

HBV-SIPA1L1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1727

Orient

-

Integrated sequence

GCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTA| |AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT

Chromosome

chr14

Cytoband

q24.2

Reference genome

Start

End

71843385/71376668 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-92a-3p ; hsa-mir-4531 ; hsa-mir-5581-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-539-5p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p

Nearest miRNA

hsa-mir-208a/Upstream/3934738; hsa-mir-1185-1/Downstream/1140152;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/55160, chr14-CpG: 114/Downstream/555279

Nearby gene

PCNX1(-261286) ; SNORD56B(+21669) ;

Upstream sequence

tttttttttagtatttattgatcattcttgggtgtttctccgagagggggatttggcagggtcataggacaatagtggagagaaggtcagcagataaaca

Downstream sequence

ggtgaacaaaggtctctggttttcctaggcagaggaccctgcggccttccttagtgtttgtgtccctgggtacttgagattagggagtggtgatgactct