Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009908
Fusion event
HBV-DNAJC17 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1688
Orient
+
Integrated sequence
CGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAA| |CGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAG
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
Start
End
41070931/40778733 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1233-1/Upstream/3805832; hsa-mir-10393/Downstream/912852;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/14144, chr15-CpG: 54/Downstream/28312
Upstream sequence
gcctataaaaaatggcttcagaggccaggtgcggcagctcaccagctgtaataccagcactttgggagactgaggtggatagcttgaggccaggagttta
Downstream sequence
agaccagcctggccaacatggtgaaactccatctctaaaaaaacggaacaaaattagccgggcgtagtggtgcatgcctgtagtcccactatcgtgaggc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.