Basic Information
VIS ID
TVIS10009912
Fusion event
HBV-chr15 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1815
Orient
-
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
End
90475471/89932239 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10393/Upstream/48209; hsa-mir-1302-10/Downstream/74516;
Nearby gene
ARPIN-AP3S2(-19249) ; ZNF710(+69281) ;
Upstream sequence
gtcataaaagaagtcaaggcagtcttaactaatggaaacccttctgccagactgtctaatggcaatttgttttctggcattgctgcttcaatgtcatctt
Downstream sequence
cctcatcgtctgggagcactcatctccatcaagatgtcttGAATCAGCAGCTTATGTTTTTAGCTTTTTCTTGCTCCTAAGTGTTGGTGGTCTTCCAGAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate